Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB in [Lv, Fang; Xiao, Jing; Xiang, Junchun; Guo, Fengzhe; Tang, Zi-Long] Hunan Univ Sci & Technol, Minist Educ, Key Lab Theoret Organ Chem & Funct Mol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China; [Han, Li-Biao] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058565, Japan published Conversion of Aryl Aldehydes to Benzyl Iodides and Diarylmethanes by H3PO3/I-2 in 2021, Cited 61. SDS of cas: 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.
For the first time, H3PO3 was used as both the reducing reagent and the promotor in the reductive benzylation reactions with aryl aldehydes. By using a H3PO3/I-2 combination, various aromatic aldehydes underwent iodination reactions and Friedel-Crafts type reactions with arenes via benzyl iodide intermediates, readily producing benzyl iodides and diarylmethanes in good yields. Intramolecular cyclization reactions also took place, giving the corresponding cyclic compounds. This new strategy features easy-handling, low-cost, and metal-free conditions.
SDS of cas: 87-41-2. About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB or concate me.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem