Condensation-cyclodehydration of 2,4-dioxobutanoates: synthesis of new esters of pyrazoles and isoxazoles and their antimicrobial screening was written by Siddiqui, Naqui Jahan;Idrees, Mohammad. And the article was included in Pharma Chemica in 2014.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:
Series of pyrazole-3-carboxylates I (X = NH, H2NCON; R1 = R3 = H, R2 = Br; R1 = Me, R2 = Cl, R3 = H, Cl; R4 = Me) and isoxazole-3-carboxylates I (X = O; R1 – R3 as above; R4 = Et) were synthesized by the reaction of 4-(benzofuran-2-yl)-2,4-dioxobutanoates II with active nitrogen nucleophiles (hydrazine hydrate, hydroxylamine hydrochloride or semicarbazide hydrochloride) via condensation-cyclodehydration sequence. The synthesized compounds I were evaluated for their antimicrobial activity against Gram pos. and Gram neg. bacteria and fungi. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem