Synthesis, characterization and biological evaluation of some pyrido[3,4-c]coumarins was written by Shaikh, Parin V.;Brahmbhatt, Dinkar I.. And the article was included in International Journal of Pharmaceutical Research and Bio-Science in 2017.Safety of 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:
The synthesis of some 2-(benzofuran-2-yl)-4-Ph pyrido[3,4-c]coumarins and 2- (furan/thiophen-2-yl)-4-Ph pyrido[3,4-c]coumarins was carried out. The compounds were synthesized by reacting various 3-benzoyl coumarins with an appropriate 2-acetylbenzofuran and 2-acetylfuran/thiophene under Kroenhke’s reaction condition. The structures of all the synthesized compounds were supported by anal. and spectral data like IR, 1H-NMR, 13C-NMR and mass. All the synthesized compounds were screened for their antimicrobial activities. The antibacterial activities were carried out against Escherichia coli and Candida albicans (Gram -ve bacteria) and Bacillus subtillis and Staphylococcus aureus (Gram +ve bacteria), while antifungal activities were carried out against fungi Candida albicans and Aspergillis niger. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Safety of 1-(5-Bromobenzofuran-2-yl)ethanone).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Safety of 1-(5-Bromobenzofuran-2-yl)ethanone
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem