In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 4265-16-1, name is Benzo[b]furan-2-carboxaldehyde, introducing its new discovery. COA of Formula: C9H6O2
A novel palladium-catalyzed selective hydroxylfluorination of gem-difluoroalkenes has been developed. By employing easily obtainable gem-difluoroalkenes and NFSI as the fluorine source, the scope, advantages, and limitations of this reaction were investigated. The reaction presents an efficient synthesis to afford a series of alpha-trifluoromethyl alcohols in good to excellent yields. Furthermore, this reaction probably proceeds via oxidation of Pd0 to PdII fluoride complex by NFSI, followed by fluoropalladation of gem-difluoroalkenes to generate an alpha-trifluoromethylbenzyl?Pd intermediate. And this strategy offers more possibilities for the construction of other bonds, such as C?C, C?N and C?S.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 4265-16-1, and how the biochemistry of the body works.COA of Formula: C9H6O2
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1128O – PubChem