On July 1, 2007, Salih, Kifah S. M.; Ayoub, Mikdad T.; Saadeh, Haythem A.; Al-Masoudi, Najim A.; Mubarak, Mohammad S. published an article.COA of Formula: C13H14O4 The title of the article was Synthesis, characterization, and biological activities of new benzofuran derivatives. And the article contained the following:
New benzofuran derivatives, Et 3-[(alkylamino)methyl]-6-methoxy-1-benzofuran-2-carboxylates, e.g., I, were obtained via the reaction between Et 3-(bromomethyl)-6-methoxy-1-benzofuran-2-carboxylate (II) and amines or amino acid Et esters. In addition, 1,4-bis[(Et 6-methoxy-1-benzofuran-3-yl-2-carboxylate)methyl]piperazine, N,N’-diethyl-N,N’-bis[(6-methoxy-1-benzofuran-3-yl-2-carboxylate) methyl]but-2-ene-1,4-diamine, and 1,2-bis[(Et 6-methoxy-1-benzofuran-3-yl-2-carboxylate)methyl]-1,2-dimethylhydrazine were also obtained from the reaction of II with diamines. Their in vitro anti-HIV-1 (strain IIIB) and HIV-2 (strain ROD) activities of the synthesized compounds in human T-lymphocyte were tested; II displayed an ability to inhibit HIV-1 and HIV-2 replication in cell culture at non-toxic concentrations The experimental process involved the reaction of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate(cas: 53724-96-2).COA of Formula: C13H14O4
The Article related to benzofurancarboxylate derivative preparation antihiv activity, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.COA of Formula: C13H14O4
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem