189035-22-1, 6-Bromo-2,3-dihydrobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 7 (4.29 g, 21.6 mmol) in THF (43 mL) was added 1.76 M t-BuLi in pentane (25.7 mL, 45.2 mmol) under Ar at -74 C. Paraformaldehyde (0.97 g, 32.3 mmol) was added to the mixture at -74 C and the mixture was stirred at room temperature overnight. The mixture was quenched with satd NH4Cl aq and extracted with AcOEt. The organic layer was washed with brine and dried over MgSO4, then filtered. After removal of the solvent, the residue was recrystallized from CH2Cl2 (6.5 mL) and n-hexane (25.9 mL) to obtain 8 as a pale red solid (2.39 g, 74%). 1H NMR (400 MHz, CDCl3) delta = 7.16 (d, J = 7.2 Hz, 1H), 6.84 (d, J = 7.2 Hz, 1H), 6.81 (s, 1H), 4.63 (br s, 2H), 4.58 (t, J = 8.8 Hz, 2H), 3.20 (t, J = 8.8 Hz, 2H); MS (ESI+) 151.1 (M+H)+., 189035-22-1
As the paragraph descriping shows that 189035-22-1 is playing an increasingly important role.
Reference£º
Article; Takahashi, Bitoku; Funami, Hideaki; Iwaki, Takehiko; Maruoka, Hiroshi; Shibata, Makoto; Koyama, Makoto; Nagahira, Asako; Kamiide, Yoshiyuki; Kanki, Satomi; Igawa, Yoshiyuki; Muto, Tsuyoshi; Bioorganic and Medicinal Chemistry; vol. 23; 15; (2015); p. 4792 – 4803;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem