4412-91-3, Name is 3-Furanmethanol, molecular formula is C5H6O2, Name: 3-Furanmethanol, belongs to benzofurans compound, is a common compound. In a patnet, author is Catinella, Giorgia, once mentioned the new application about 4412-91-3.
Structural Requirements of Benzofuran Derivatives Dehydro-delta- and Dehydro-epsilon-Viniferin for Antimicrobial Activity Against the Foodborne Pathogen Listeria monocytogenes
In a recent study, we investigated the antimicrobial activity of a collection of resveratrol-derived monomers and dimers against a series of foodborne pathogens. Out of the tested molecules, dehydro-delta-viniferin and dehydro-epsilon-viniferin emerged as the most promising derivatives. To define the structural elements essential to the antimicrobial activity against the foodborne pathogen L. monocytogenes Scott A as a model Gram-positive microorganism, the synthesis of a series of simplified benzofuran-containing derivatives was carried out. The systematic removal of the aromatic moieties of the parent molecules allowed a deeper insight into the most relevant structural features affecting the activity. While the overall structure of compound 1 could not be altered without a substantial loss of antimicrobial activity, the structural simplification of compound 2 (minimal inhibitory concentration (MIC) 16 mu g/mL, minimal bactericidal concentration (MBC) >512 mu g/mL) led to the analogue 7 with increased activity (MIC 8 mu g/mL, MBC 64 mu g/mL).
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 4412-91-3. The above is the message from the blog manager. Name: 3-Furanmethanol.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem