Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 14400-67-0, Name is 2,5-Dimethylfuran-3(2H)-one, molecular formula is , belongs to benzofurans compound. In a document, author is Sedano, Carlos, Product Details of 14400-67-0.
alpha-Lithiobenzyloxy as a Directed Metalation Group in ortho-Lithiation Reactions
The alpha-lithiobenzyloxy group, easily generated from aryl benzyl ethers by selective alpha-lithiation with t-BuLi at low temperature, behaves as a directed metalation group (DMG) providing a direct access to o-lithiophenyl alpha-lithiobenzyl ethers. This ortho-directing effect is reinforced in substrates bearing an additional methoxy group at the meta position. The generated dianions can be reacted with a selection of electrophiles including carboxylic esters and dihalosilanes or germanes, which afford interesting benzofuran, sila(germa)dihydrobenzofuran, and silachroman derivatives from simple aryl benzyl ethers.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem