In an article, author is Wang, Cheng-Jie, once mentioned the application of 87-41-2, Name is Isobenzofuran-1(3H)-one, molecular formula is C8H6O2, molecular weight is 134.13, MDL number is MFCD00005906, category is benzofurans. Now introduce a scientific discovery about this category, SDS of cas: 87-41-2.
Catalytic asymmetric 1,4-type Friedel-Crafts (hetero)arylations of 1-azadienes: the highly enantioselective syntheses of chiral hetero-triarylmethanes
Direct enantioselective Michael-type Friedel-Crafts arylations and heteroarylations of s-cis 1-azadienes were achieved by applying chiral bifunctional tertiary amine-urea catalysts when using 2-naphthols as the nucleophiles, and phosphoric acid catalysts when using indoles as the nucleophiles. These two catalytic protocols efficiently enabled access to a diverse variety of important benzofuran-containing hetero-triarylmethanes in up to 98% yield and with 99.5 : 0.5 er.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem