Fluorogenic Quantification of Albumin was written by Low, Michelle;Win, Khin Yin;Ye, Enyi;Liu, Shuhua;Ng, Soon Huat;Zhou, Xiaoqun;Han, Ming-Yong. And the article was included in Australian Journal of Chemistry in 2014.Recommanded Product: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione This article mentions the following:
By optimizing various fluorogenic dyes, non-fluorescent fluorescamine can react with primary amines to form highly fluorescent products, which is a simple, fast, and sensitive method for the quantification of albumin. The effects of pH, temperature, and chems. were studied systematically to quantify albumin. The quantification method is more sensitive at alk. pHs, affording measurement of proteins concentrations as low as 15 μg mL-1. Denaturation of albumin at elevated temperatures and/or use of chems., such as ethanol and acetone, can greatly improve the sensitivity of the albumin detection method. The simple, accurate, and reliable anal. of albumin contents under favorable conditions can be developed as an important method for early diagnosis of kidney disease. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Recommanded Product: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione).
4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Recommanded Product: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem