《Semiconductor ZnO based photosensitizer core-shell upconversion nanoparticle heterojunction for photodynamic therapy》 was written by Li, Yongmei; Li, Yuemei; Bai, Yandong; Wang, Rui; Lin, Laixiang; Sun, Yina. Quality Control of 1,3-DiphenylisobenzofuranThis research focused onzinc oxide photosensitizer nanoparticle heterojunction photodynamic therapy. The article conveys some information:
Photodynamic therapy (PDT) as a noninvasive technique is widely used to treat cancer diseases due to its low side effects. PDT based on upconversion nanoparticles (UCNPs) improved tissue penetration and photo-stability. However, traditional photosensitizers and UCNPs were difficult to incorporate, which limited the circulation of the UCNPs in blood and decreased the PDT effect. Herein, we designed NaErF4@ZnO UCNPs for potential application in thyroid tumor cell PDT. With ZnO coated on NaErF4, the blue (415 nm), green (525 nm/545 nm) and red (661 nm) upconversion luminescence enhanced compared with that of NaErF4 core nanoparticles. Particularly, the generation of UV upconversion emission by NaErF4 sensitized ZnO, which catalyzed H2O and O2 to produce ROS reactive oxygen species (ROS) to induce papillary thyroid carcinoma (PTC) cell lines BHP 5-16. With 1000μg mL-1 of NaErF4@ZnO UCNPs, the viability of BHP 5-16 cells decreased to about 41% as measured by CCK8 assay with 980 nm NIR irradiation Moreover, it was confirmed that NaErF4@ZnO UCNPs had low toxicity for BHP 5-16 cells. All these results indicated that NaErF4@ZnO upconversion nanoparticles were an excellent platform for PDT treatment. The experimental process involved the reaction of 1,3-Diphenylisobenzofuran(cas: 5471-63-6Quality Control of 1,3-Diphenylisobenzofuran)
1,3-Diphenylisobenzofuran(cas: 5471-63-6) is a fluorescent dye. 1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.Quality Control of 1,3-Diphenylisobenzofuran
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem