Thermoresponsive Dynamic Covalent Polymers with Tunable Properties was written by Li, Jingyi;Yang, Shixia;Wang, Lin;Wang, Xiaobei;Liu, Li. And the article was included in Macromolecules (Washington, DC, United States) in 2013.HPLC of Formula: 3326-34-9 This article mentions the following:
A bisaldehyde-containing trithiocarbonate chain transfer agent was prepared and mediated the synthesis of polymers with bisaldehyde-functionalized α-termini by reversible addition-fragmentation chain transfer (RAFT) radical polymerization The α-termini of RAFT-derived thermoresponsive poly-(N-isopropylacrylamide) was conjugated with hydrazides via reversible acylhydrazone bonds. Introduction of hydrophilic end-groups generated a dynamic covalent polymer with “isothermal” lower critical solution temperature (LCST) response to medium pH and dynamic chain exchange character. A biofunctional dynamic covalent polymer was prepared by conjugation with biotin hydrazide. Under appropriate reaction conditions, a dynamic covalent block copolymer with an aldehyde group at the junction point was constructed through a reversible arylhydrazone linkage by coupling with acylhydrazide-terminated poly-(ethylene glycol). The dynamic covalent block copolymer exhibited pH-dependent LCST. The remaining aldehyde group was used to react with amino-containing mols. Bioconjugated dynamic covalent block copolymers containing reversible imine and arylhydrazone linkages were constructed by conjugation of the block copolymer to glucosamine and protein. In the experiment, the researchers used many compounds, for example, 5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9HPLC of Formula: 3326-34-9).
5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.HPLC of Formula: 3326-34-9
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem