Microwave assisted synthesis and pharmacological evaluation of some potent naphthofuryl- and benzofurylthiazole, -oxazole, -thiadiazine and -oxadiazine derivatives was written by Kumar, D. B. Aruna;Prakash, G. K.;Nandeshwarappa, B. P.;Kiran, B. M.;Sherigara, B. S.;Mahadevan, K. M.. And the article was included in Indian Journal of Pharmaceutical Sciences in 2006.Synthetic Route of C10H7BrO2 This article mentions the following:
Bromination of substituted 2-acetylbenzofurans gave substituted 2-(2-bromoacetyl)benzofurans. 2-(2-Bromoacetyl)benzofurans reacted with thiourea, urea, thiosemicarbazide and semicarbazide in presence of sodium acetate under microwave irradiation to give heterocyclyl benzo- and naphthofuran derivs, e.g., I and II. The structures of synthesized compounds have been established by elemental anal., spectral data. All the synthesized compounds were screened for antimicrobial, anthelmintic, antiinflammatory and analgesic activities. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Synthetic Route of C10H7BrO2).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Synthetic Route of C10H7BrO2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem