Synthesis, characterization, antimicrobial and in-silico studies of (1,1-dibenzofuran-2-yl) ethyl terephthalamide derivatives was written by Gurunathan, Krishnaswamy;R., Desai Nivedita;Hanuma, Naika Raja Naika;B., Aruna Kumar Doyijode;S., Sreenivasa. And the article was included in Research Journal of Chemistry and Environment in 2021.HPLC of Formula: 38220-75-6 This article mentions the following:
In search of new benzofuran derivatives of biol. importance, sym. terephthalamide derivatives I [R = H, Cl, Br; R1 = H, Cl, Br] of benzofuran were synthesized from 2- acetylbenzofuran. The synthesis of title compounds followed a sequence of condensation, reduction and coupling reactions. The structures of all the newly synthesized compounds were established by FT-IR, 1H and 13C NMR and MS spectral methods. The formation of amine follows novel reduction method under microwave irradiation All the synthesized compounds I, II and III were subjected to invitro antimicrobial studies and found to be moderate antibacterial agent and poor antifungal agents. In correlation, the mode of action of these compounds I, II and III as antimicrobial agents was determined by the in-silico studies. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6HPLC of Formula: 38220-75-6).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.HPLC of Formula: 38220-75-6
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem