Application of CGE to virus identification was written by Fruetel, Julia A.;Vander Noot, Victoria A.. And the article was included in Methods in Molecular Biology (New York, NY, United States) in 2013.Reference of 38183-12-9 This article mentions the following:
Protein profiling is an increasingly valuable tool for the characterization of protein populations and has been used to identify microorganisms, most often using two-dimensional gel electrophoresis followed by mass spectrometry. We present a rapid method for the identification of viruses using microfluidic chip gel electrophoresis (CGE) of high-copy number proteins to generate unique protein profiles. Viral proteins are solubilized, fluorescently labeled and then analyzed using the μChemLab CGE system (â?0 min overall). A Bayesian classification approach is used to classify the reproducible and visually distinct protein profiles of MS2 bacteriophage, Epstein-Barr, Respiratory Syncytial, and Vaccinia viruses as well as discriminate between closely related T2 and T4 bacteriophage. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Reference of 38183-12-9).
4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Reference of 38183-12-9
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem