One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 41019-56-1, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 41019-56-1, Name is Methyl benzofuran-4-carboxylate, molecular formula is C10H8O3
Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles
Replacing the naphthalene C-unit of the anti-tuberculosis drug bedaquiline with a range of bicyclic heterocycles of widely differing lipophilicity gave analogs with a 4.5-fold range in clogP values. The biological results for these compounds indicate on average a lower clogP limit of about 5.0 in this series for retention of potent inhibitory activity (MIC90s) against M.tb in culture. Some of the compounds also showed a significant reduction in inhibition of hERG channel potassium current compared with bedaquiline, but there was no common structural feature that distinguished these.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. SDS of cas: 41019-56-1, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 41019-56-1, in my other articles.
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2802O – PubChem