Extended knowledge of 27550-59-0

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 27550-59-0 is helpful to your research. Reference of 27550-59-0

Reference of 27550-59-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 27550-59-0, molcular formula is C8H4O4, introducing its new discovery.

Objectives The purpose of this work was to study the chemical stability of the new antitumoral beta-lapachone (betaLAP) to determine the degradation pathway/s of the molecule and the degradation kinetics in addition to identifying several degradation products. Method Samples of betaLAP in solution were stored under conditions of darkness and illumination at 40C at which the pseudo-first order rate constants for the betaLAP degradation were determined. Furthermore, drug degraded solutions were concentrated and purified using Sephadex LH-20 and preparative thin-layer chromatography and degradation products were identified by nuclear magnetic resonance spectroscopy. Key findings The results revealed that betaLAP shows two different degradation routes: hydrolysis in the dark and photolysis under the light. The betaLAP exposure to light accelerated the drug degradation about 140 fold, compared with the samples stored in the absence of light. The hydrolysis produced hydroxylapachol as the main degradation product. The photolysis yielded phthalic acid, 6-hydroxy-3methylene-3H-isobenzofuran-1-one and a benzomacrolactone together with a complex mixture of other phthalate-derivatives such as 2-(2-carboxy-acetyl)-benzoic acid. Conclusions This study provides useful information for the development of betaLAP dosage forms, their storage, manipulation and quality control.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 27550-59-0 is helpful to your research. Reference of 27550-59-0

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2144O – PubChem