Extended knowledge of 2-(Benzofuran-3-yl)ethanamine

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Product Details of 27404-31-5, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 27404-31-5, name is 2-(Benzofuran-3-yl)ethanamine. In an article,Which mentioned a new discovery about 27404-31-5

NMDA receptors are tetrameric complexes composed of GluN1 and GluN2A-D subunits that mediate a slow Ca2+-permeable component of excitatory synaptic transmission. NMDA receptors have been implicated in a wide range of neurological diseases and thus represent an important therapeutic target. We herein describe a novel series of pyrrolidinones that selectively potentiate only NMDA receptors that contain the GluN2C subunit. The most active analogues tested were over 100-fold selective for recombinant GluN2C-containing receptors over GluN2A/B/D-containing NMDA receptors as well as AMPA and kainate receptors. This series represents the first class of allosteric potentiators that are selective for diheteromeric GluN2C-containing NMDA receptors.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H1611O – PubChem