Reference of 17403-47-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 17403-47-3, 5-Nitro-2,3-dihydrobenzofuran, introducing its new discovery.
Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics
Syntheses and structure-activity relationships (SAR) of nonsteroidal glucocorticoid receptor (GR) agonists are described. These compounds contain azaindole moieties as A-ring mimetics and display various degrees of in vitro dissociation between gene transrepression and transactivation. Collagen induced arthritis studies in mouse have demonstrated that in vitro dissociated compounds (R)-16 and (R)-37 have steroid-like anti-inflammatory properties with improved metabolic side effect profiles, such as a reduced increase in body fat and serum insulin levels, compared to steroids.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 17403-47-3. In my other articles, you can also check out more blogs about 17403-47-3
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2449O – PubChem