Dej-adisai, Sukanya published the artcileDetermination of phytochemical compounds, and tyrosinase inhibitory and antimicrobial activities of bioactive compounds from Streblus ilicifolius (s vidal) corner, Computed Properties of 56317-21-6, the publication is Tropical Journal of Pharmaceutical Research (2016), 15(3), 497-506, database is CAplus.
Purpose: To determine the phytochem. content, and tyrosinase inhibitory and antimicrobial activities of the wood from S treblus ilicifolius (S. Vidal) Corner Methods: The dried wood of S. ilicifolius (8.70 kg) was extracted by maceration to give petroleum ether, Et acetate, ethanol and water extracts, resp. Dopachrome method was used to determine antityrosinase activity. Agar disk diffusion and modified broth microdilution methods were used to determine antimicrobial activity. Chromatog. techniques were used for phytochem. investigation. The structures elucidation of isolated compounds were identified by phys. properties and spectroscopic data including UV, IR, NMR and MS data and confirmed by comparison with previously reports. Results: The ethanol extract exhibited tyrosinase inhibition and antimicrobial activity against the Grampos. bacteria, Staphylococcus epidermidis and S. aureus. Phytochem. investigation showed five compounds, namely, (E)-2,4-dihydroxy-3-(3,7-dimethyl-2,6-octadienyl) benzaldehyde (1), phydroxybenzoic acid Me ester (2), umbelliferone (3), moracin M (4), trans-resveratrol (5). Compound 4 exhibited tyrosinase inhibition with half maximal inhibitory concentration (IC50) of 67.69 μg/mL, while compound 1 displayed strong activity against S. epidermidis, S. aureus and methicillin-resistant S. aureus (MRSA) with min. inhibitory concentration (MIC) of 8, 4 and 8 μg/mL, resp. and min. bactericidal concentration (MBC) of 32, 16 and 64 μg/mL, resp. Conclusion: This is the first report of the biol. activities and phytochem. composition of S. ilicifolius and the results indicate the high potentials of the plant for com. applications such as in facial whitening and anti-acne cream.
Tropical Journal of Pharmaceutical Research published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem