Chishti, Benazir et al. published their research in Materials Today: Proceedings in 2021 | CAS: 76-54-0

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Formula: C20H10Cl2O5

Engineered nano-ZnO: Doping regulates dissolution and reactive oxygen species levels eliciting biocompatibility was written by Chishti, Benazir;Ansari, Z. A.;Ansari, S. G.. And the article was included in Materials Today: Proceedings in 2021.Formula: C20H10Cl2O5 This article mentions the following:

Nano-ZnO being a pre-dominant constituent in every-day utility products encourages to strive for safety. This study was aimed to fill the knowledge gap concerning on mechanism of nano-ZnO toxicity and develop strategies to curb. Synthesized pristine ZnO nanocrystals (NCs) and doping of Fe and Mn in nano-ZnO was characterized for cytotoxicity, reactive oxygen species (ROS) and biotic dissolution traits in Gram-pos. (Staphylococcus aureus) and Gram-neg. (Escherichia coli) bacterial cells. Zinc ions (Zn2+) dissolution and ROS production found responsible in stating toxicol. effects of nano-ZnO in E. coli cells. Over Mn (1.09*1022), doping of metal (Fe) atom (1.1*1022) in ZnO lattice introduces kinetic constraints for the release of Zn2+ ions recovered in bacterial pellet which lowers dissolution rate leading low ROS and lipid peroxidation (LPO), delivers high min. inhibitory concentration (MIC) in both the bacterial cells. Fe doped ZnO NCs also demonstrate effective protective potential in oxidative challenged bacterial cells, with least effect on growth rate, percentage cell viability, membrane damage and ROS production Further, hemo-compatible response biocompatibility assessed in human red blood cells shows negligible release of Hb (Hb < 12%). In the experiment, the researchers used many compounds, for example, 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0Formula: C20H10Cl2O5).

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Formula: C20H10Cl2O5

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem