In-vivo study of metabolism of trifolirhizin in rats was written by Chen, Lei;Liu, Yi;Zhang, Honggui;Liang, Shengwang. And the article was included in Zhongyao Xinyao Yu Linchuang Yaoli in 2012.Product Details of 6807-83-6 This article mentions the following:
Objective: To investigate the principal metabolites of trifolirhizin in rats after intragastric (ig) administration by HPLC-MSn, and to propose their metabolic pathways. Methods: Urine and stool of the rats were collected after administration for the comprehensive anal. of chromatog. retention time and electrospray mass spectrometry and multistage level information of the metabolites, and the results were compared with the reference substance. Results: Maackiain and maackiain-3-O-sulfoacid were identified in urine, and maackiain was identified in feces after trifolirhizin ig administration. Conclusion: Extensive metabolism of trifolirhizin has been shown in rats after ig administration, and the metabolic pathway of the metabolites has been proposed. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6Product Details of 6807-83-6).
(2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Product Details of 6807-83-6
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem