Chen, Hong-Bin’s team published research in Asian Journal of Organic Chemistry in 5 | CAS: 56317-21-6

Asian Journal of Organic Chemistry published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Product Details of C14H10O4.

Chen, Hong-Bin published the artcileAccessing 2-Arylbenzofurans by CuI2(pip)2-Catalyzed Tandem Coupling/Cyclization Reaction: Mechanistic Studies and Application to the Synthesis of Stemofuran A and Moracin M, Product Details of C14H10O4, the publication is Asian Journal of Organic Chemistry (2016), 5(11), 1345-1352, database is CAplus.

An asym. dinuclear copper(I) complex, CuI2(pip)2 (pip = (2-picolyliminomethyl)pyrrole anion), was utilized to catalyze the tandem coupling/cyclization reaction of o-iodophenols and terminal alkynes, which led to the formation of valuable 2-arylbenzofurans I (R1 = Ph, 4-EtC6H4, 1-naphthyl, etc.; R2 = H, 4-MeO, 4-t-Bu, 4-Ph, 4-F, 4-Br) in good yields. DFT calculations showed that the two proximate copper atoms play cooperative roles throughout the catalytic cycle. Using this catalytic protocol, bioactive natural products stemofuran A and moracin M were concisely synthesized.

Asian Journal of Organic Chemistry published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Product Details of C14H10O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem