496-41-3, Name is Benzofuran-2-carboxylic acid, belongs to benzofuran compound, is a common compound. Application In Synthesis of Benzofuran-2-carboxylic acidIn an article, once mentioned the new application about 496-41-3.
Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)
We report the synthesis and evaluation of a series of heterobiaryl amides as positive allosteric modulators of mGluR4. Compounds 9b and 9c showed submicromolar potency at both human and rat mGluR4. In addition, both 9b and 9c were shown to be centrally penetrant in rats using nontoxic vehicles, a major advance for the mGluR4 field.
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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1792O – PubChem