Bilger, Christine et al. published their research in European Journal of Medicinal Chemistry in 1987 | CAS: 33094-66-5

2-Nitrobenzofuran (cas: 33094-66-5) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Name: 2-Nitrobenzofuran

Modifications of biological activity following the addition of a second nitrofuran ring to nitroarenofuran homocycles was written by Bilger, Christine;Demerseman, Pierre;Buisson, Jean Pierre;Royer, Rene;Gayral, Philippe;Fourniat, Jacky. And the article was included in European Journal of Medicinal Chemistry in 1987.Name: 2-Nitrobenzofuran This article mentions the following:

2,7-Dinitrobenzo[1,2-b:4,3-b‘]difuran (I) was prepared by the direct nitration of II and the derivatives nitrated in the α-positions of the heterocycles, naphtho[2,1-b:7,6-b‘]difuran, naphtho[2,1-b:6,5-b‘]difuran, naphtho[1,2-b:5,6-b‘]difuran and anthra[2,1-b:6,5-b‘]difuran were obtained by the condensation of bromonitromethane with the appropriate bis[ortho-hydroxy(formyl)]naphthalenes or -anthracene. The antibacterial and antiprotozoal activity of these compounds was compared with that of condensed systems containing a single furan ring (e.g., 2-nitrobenzofuran, 2-nitronaphtho[2,1-b]furan, etc.). Trichomonas vaginalis, Entamoeba histolytica, Staphylococcus aureus, And Escherichia coli were used as the test organisms. The dinitroarenodifurans were more active against the microorganisms than the nitroarenofurans. In the experiment, the researchers used many compounds, for example, 2-Nitrobenzofuran (cas: 33094-66-5Name: 2-Nitrobenzofuran).

2-Nitrobenzofuran (cas: 33094-66-5) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Name: 2-Nitrobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem