Baumgartner, Maria T. et al. published their research in Journal of Organic Chemistry in 1993 | CAS: 205-39-0

Naphtho[2,1-b]benzofuran (cas: 205-39-0) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Synthetic Route of C16H10O

Photostimulated reactions of o-dihalobenzenes with nucleophiles derived from the 2-naphthyl system. Competition between electron transfer, fragmentation, and ring closure reactions was written by Baumgartner, Maria T.;Pierini, Adriana B.;Rossi, Roberto A.. And the article was included in Journal of Organic Chemistry in 1993.Synthetic Route of C16H10O This article mentions the following:

The photostimulated reaction of o-XC6H4Y (I; X = I, Br, Cl, Y = I; X = Cl, Y = Br) with 2-naphthoxide (II, Z = O) gave 1-(o-halophenyl)-2-naphthol (III; halo = I, Br, Cl) and ring-closure product IV (Z = O), III being an intermediate in the formation of IV (Z = O). The products obtained in the photostimulated reaction of II (Z = S) with I depended on the halogens. When both nucleofugal groups were iodine, only IV (Z = S) was obtained. With o-bromoiodobenzene, the photostimulated reaction gave IV (Z = S) and the substitution product on sulfur with retention of bromine, while with o-chloroiodobenzene the only observed product was the substitution product on sulfur with retention of chlorine. The photostimulated reaction of I with II (Z = Se) gave the same amount of cyclized product IV (Z = Se) and the substitution product on selenium without retention of halogen, although in an overall low yield. All these reactions may occur by the SRN1 mechanism. Theor. studies supported the different behavior found with the nucleophiles derived from the 2-naphthyl system. In the experiment, the researchers used many compounds, for example, Naphtho[2,1-b]benzofuran (cas: 205-39-0Synthetic Route of C16H10O).

Naphtho[2,1-b]benzofuran (cas: 205-39-0) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Synthetic Route of C16H10O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem