Electric Literature of 90843-31-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.90843-31-5, Name is 5-Acetyl-2,3-dihydrobenzo[b]furan, molecular formula is C10H10O2. In a Article，once mentioned of 90843-31-5
Protein kinase B (PknB) is an essential serine/threonine protein kinase required for Mycobacterium tuberculosis (M. tb) cell division and cell-wall biosynthesis. A high throughput screen using PknB identified a (E)-4-oxo-crotonic acid inhibitor, named YH-8, which was used as a scaffold for SAR investigations. A significant improvement in enzyme affinity was achieved. The results indicated that the alpha,beta-unsaturated ketone scaffold and ?trans-? configuration are essential for the activity against PknB. And compounds with an aryl group, especially with electron-withdrawing substituents on benzene ring, exhibited four fold potency than that of YH-8.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 90843-31-5
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2098O – PubChem