SDS of cas: 87-41-2. In 2020 ACS CATAL published article about ASYMMETRIC BINARY ACID; 3-SUBSTITUTED PHTHALIDES; TRANSFER HYDROGENATION; RELAY CATALYSIS; TRANSFORMATION; DERIVATIVES; FUSCINARIN; CHEMISTRY; ACETALS; ETHERS in [Pan, Yu-Liang; Zheng, Han-Liang; Wang, Jie; Yang, Chen; Li, Xin; Cheng, Jin-Pei] Nankai Univ, State Key Lab Elementoorgan Chem, Coll Chem, Tianjin 300071, Peoples R China in 2020, Cited 81. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.
Phthalides as the crucial core skeletons are found extensively in natural products and biological active molecules. Herein we disclose an asymmetric allylation of 3-hydroxyisoben-zofuran-1(3H)-ones with boron allylation reagents to construct chiral phthalide derivatives. The simple Bi(OAc)(3)/chiral phosphoric acid catalytic system proves to be efficient in this method, delivering the desired chiral 3-allylisobenzofuran-1(3H)-ones in good yields (up to 99%) and high enantioselectivities (up to 99.5:0.5 e.r.) under mild conditions. The large-scale reaction and diverse transformations of products to various scaffolds with potential biological activities render it more attractive. Moreover, the mechanism was preliminarily explored by control reactions, mass spectrometry, deuterium experiment, and DFT calculations.
SDS of cas: 87-41-2. About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Pan, YL; Zheng, HL; Wang, J; Yang, C; Li, X; Cheng, JP or concate me.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem