496-41-3, Name is Benzofuran-2-carboxylic acid, belongs to benzofurans compound, is a common compound. HPLC of Formula: C9H6O3In an article, once mentioned the new application about 496-41-3.
The invention provides 1-(1-imido)-2-aryl methyl-1,2,3,4-tetrahydroisoquinoline derivatives and a preparation method and application thereof. Stirring is conducted for 10-24 h at a certain temperature in organic solvent methylbenzene with 1,2,3,4-tetrahydroisoquinoline, aldehyde, carboxylic acid and isonitrile as raw materials and molecular sieves as additives. High-purity 1-(1-imido)-2-aryl methyl-1,2,3,4-tetrahydroisoquinoline derivatives are obtained after vacuum concentration, column chromatography and other operation are conducted on reaction mixed liquid. Raw materials are easy to obtain, reaction conditions are mild, and operation is easy; 1-(1-imido)-2-aryl methyl-1,2,3,4-tetrahydroisoquinoline derivatives with various substituent groups are easy to obtain, the requirement of high-flux sieving for tetrahydroisoquinoline derivatives can be well met, and great application and market value is achieved.
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1686O – PubChem