Archives for Chemistry Experiments of 3-Aminobenzofuran-2-carboxamide

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 54802-10-7, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 54802-10-7, Name is 3-Aminobenzofuran-2-carboxamide, molecular formula is C9H8N2O2

The displacement reaction of 2-(4-N,N-dimethyl/nitrophenyl)-4-oxo-benzofuro [3,2-d] pyrimidine 1-2 with phosphorus oxychloride yielded 2-(4-N,N-dimethyl/ nitrophenyl)-4- chlorobenzofuro [3,2-d] pyrimidines 3-4. 2-[4-N,N-Dimethyl/ nitrophenyl]-4- hydrazinobenzofuro [3,2-d] pyrimidines 5-6 were prepared by the reaction of 3-4 with hydrazine hydrate. Compounds 5-6 upon treatment with sodium azlde and triethylorthoformate gave 5-(4-N,N-dimethyl/nitrophenyl)-triazoio [4,3-c] pyrimido [5,4- b] benzofurans 7-8 and 5-(4-N,N-dimethyl/nitrophenyl)- triazolo [1,5-c] pyrimido [5,4-b] benzofurans. 9-10.4-Hydrazino compounds 5-6 were also subjected to condensation with aromatic aldehydes which afforded 2-(4-N,N-dimethyl/nitrophenyl)-4-arylidene hydrazinobenzofuro [3,2-d] pyrimidines 11-20. All synthesized compounds were characterized on the basis of spectral studies and further these compounds were evaluated for antimicrobial and antitubercular activities.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2815O – PubChem