Analyzing the synthesis route of 7168-85-6

7168-85-6 7-Methoxybenzofuran 590462, abenzofuran compound, is more and more widely used in various fields.

7168-85-6, 7-Methoxybenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,7168-85-6

A mixture of 500 mg (3.38 mmol) 7-methoxy-1 -benzofuran in anhydrous THF (30 mL) was cooled to -78 C. 3.2 mL (5 mmol) of a 1.6 M solution of n-butyllithium in hexane was added and the resulting mixture stirred for 1 h at -78C. 1.37 mL (5 mmol) of tributyltin chloride was added. The reaction was stirred at rt over night. Methanol was carefully added and the solvent evaporated. The obtained residue was purified by flash chromatography to yield 1.3 g of crude product of the corresponding 2-stannylbenzofurane, which was used without further purification.

7168-85-6 7-Methoxybenzofuran 590462, abenzofuran compound, is more and more widely used in various fields.

Reference£º
Patent; Bayer Intellectual Property GmbH; EIS, Knut; PUeHLER, Florian; ZORN, Ludwig; SCHOLZ, Arne; LIENAU, Philip; GNOTH, Mark, Jean; BOeMER, Ulf; GUeNTHER, Judith; HITCHCOCK, Marion; WO2013/34570; (2013); A1;,
Benzofuran – Wikipedia
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