Recently I am researching about FRIEDEL-CRAFTS ALKYLATION; CYCLIZATION; HALIDES; ARENES; ACID; NUCLEOPHILES; ALCOHOLS; BROMIDES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21703061]. Application In Synthesis of Isobenzofuran-1(3H)-one. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one
For the first time, H3PO3 was used as both the reducing reagent and the promotor in the reductive benzylation reactions with aryl aldehydes. By using a H3PO3/I-2 combination, various aromatic aldehydes underwent iodination reactions and Friedel-Crafts type reactions with arenes via benzyl iodide intermediates, readily producing benzyl iodides and diarylmethanes in good yields. Intramolecular cyclization reactions also took place, giving the corresponding cyclic compounds. This new strategy features easy-handling, low-cost, and metal-free conditions.
Welcome to talk about 87-41-2, If you have any questions, you can contact Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB or send Email.. Application In Synthesis of Isobenzofuran-1(3H)-one
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem