An update on the compound challenge: C8H6O2

About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Wang, J; Li, X; Cheng, JP or concate me.. COA of Formula: C8H6O2

I found the field of Chemistry very interesting. Saw the article Quinine-derived thiourea promoted enantioselective Michael addition reactions of 3-substituted phthalides to maleimides published in 2019. COA of Formula: C8H6O2, Reprint Addresses Li, X (corresponding author), Nankai Univ, State Key Lab Elementoorgan Chem, Collaborat Innovat Ctr Chem Sci & Engn, Coll Chem, Tianjin 300071, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

A highly diastereoselective and enantioselective Michael addition/desymmetrization reaction of maleimides with prochiral 3- substituted phthalides catalyzed by quinine-derived bifunctional thiourea was realized. A broad range of the 3,3-disubstituted phthalides bearing vicinal quaternary-tertiary stereogenic centers were synthesized in moderate to good yields (up to 96%) with high diastereoselectivities (up to >19:1 dr) and enantioselectivities (up to 96:4 er).

About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Wang, J; Li, X; Cheng, JP or concate me.. COA of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem