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We report here on the screening of a fragment library against a G-quadruplex element in the human c-MYC promoter. The ten fragment hits had significant concordance between a biophysical assay, in silico modelling and c-MYC expression inhibition, highlighting the feasibility of applying a fragment-based approach to the targeting of a quadruplex nucleic acid.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 58546-89-7, and how the biochemistry of the body works.Related Products of 58546-89-7

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H387O – PubChem