A new application about 16859-59-9

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Reference of 16859-59-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16859-59-9, Name is 3-Hydroxyisobenzofuran-1(3H)-one, molecular formula is C8H6O3. In a Article£¬once mentioned of 16859-59-9

Non-cryogenic metalation of aryl bromides bearing proton donating groups: Formation of a stable magnesio-intermediate

Bromine-metal exchange of o-bromobenzoic acid (1) with Bu2Mg followed by n-BuLi was successfully carried out at non-cryogenic temperature (>-20C), and gave a stabilized metal species which smoothly reacted with several electrophiles. This methodology expanded to several other bromides bearing proton donating groups (PDGs).

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1465O – PubChem