Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 5-Methoxybenzofuran-2-carboxylic acid, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 10242-08-7
Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups
The seco-Cl 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) derivatives dl- and/or (S)-10 carrying various acyl moleties at the N6-position were synthesized along with their prodrugs (S)-12, and their antitumor activity was evaluated. Among these derivatives, AT-3510 [(S)- 12m], the novel prodrug MCTFCPI derivative carrying a 5-(7- methoxybenzofuran-2-ylcarbonyl)aminoindole-2-carbonyl group at the N6- position, was found to exhibit more excellent antitumor activity against human tumor xenografts than the clinical trial candidates carzelesin (6) and KW-2189 (7) and cisplatin.
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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3109O – PubChem