9/28/2021 News Discovery of 496-41-3

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Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: Benzofuran-2-carboxylic acid, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 496-41-3

Two novel classes of diphenyloxazole and Ndelta-Z-ornithine derivatives as highly potent and selective EP4 antagonists have been discovered. The optimized diphenyloxzole 8 and Ndelta-Z-ornithine 11 effectively competed with [3H]-PGE2 binding to human recombinant EP 4, with Ki values of 0.30 nM and 0.91 nM, respectively, and were selective for all members of the human prostanoid receptor family. 8 was shown to exhibit good pharmacokinetic properties in rats and dogs and potent inhibitory activity toward in vitro PGE2-promoted IgE synthesis.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H1810O – PubChem