In heterogeneous catalysis, the catalyst is in a different phase from the reactants. name: 5-Methoxybenzofuran-3(2H)-one, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 39581-55-0, name is 5-Methoxybenzofuran-3(2H)-one. In an article，Which mentioned a new discovery about 39581-55-0
A series of substituted racemic naphthofurans were synthesized as ‘hybrid’ molecules of the two major prototypical hallucinogenic drug classes, the phenethylamines and the tryptamines/ergolines. Although it was hypothesized that these new agents might possess high affinity for the serotonin 5-HT(2A)/(2C) receptor subtypes, unexpected affinity for muscarinic receptors was observed. The compounds initially synthesized for this study were (±)-anti- and syn-4-amino-6-methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8- bc]furan (4a,b), respectively, and their 8-bromo derivatives 4c,d, respectively. The brominated primary mines 4c,d were assayed initially for activity in the two-lever drug discrimination (DD) paradigm in rats trained to discriminate saline from LSD tartrate (0.08 mg/kg). Also, 4c,d were evaluated for their ability to compete against agonist and antagonist radioligands at cloned human 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptors. After the syn diastereomers were found to have the highest activity in these preliminary assays, the N-alkylated analogues syn-N,N-dimethyl-4-amino-6- methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8-bc]furan (4e) and syn-N,N- dipropyl-4-amino-6-methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8-bc]furan (4f) were prepared and assayed for their affinities at [3H]ketanserin-labeled 5- HT(2A) and [3H]-8-OH-DPAT-labeled 5-HT(1A) sites. All of the molecules tested had relatively low affinity for serotonin receptors, yet a preliminary screen indicated that compound 4d had affinity for muscarinic receptors. Thus, 4b,d,e were evaluated for their affinity at muscarinic M1-M5 receptors and also assessed for their functional characteristics at the M1 and M2 isoforms. Compound 4d had affinities of 12-33 nM at all of the muscarinic sites, with 4b,e having much lower affinity. All three compounds fully antagonized the effects of carbachol at the M1 receptor, while only 4d completely antagonized carbachol at the M2 receptor. The fact that the naphthofurans lack LSD-like activity suggests that they do not bind to the serotonin receptor in a way such that the tricyclic naphthofuran nucleus is bioisosteric with, and directly superimposable upon, the A, B, and C rings of LSD. This also implies, therefore, that the hallucinogenic phenethylamines cannot be directly superimposed on LSD in a common binding orientation for these two chemical classes, contrary to previous hypotheses.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 39581-55-0, help many people in the next few years.name: 5-Methoxybenzofuran-3(2H)-one
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2240O – PubChem