Screening of medicinal plants: Rheum emodi induces interferon stimulated gene 56 (IFIT1), a antiviral protein was written by Naresh, Damuka;Saikia, Paramananda;Meetei, Potshangbam Angamba;Kanta, Abhishek;Vindal, Vaibhav. And the article was included in International Journal of Pharma Research and Health Sciences in 2018.Electric Literature of C16H10O7 The following contents are mentioned in the article:
Medicinal plants are important sources of medicines for healthcare. Several plants could offer a rich resource for agonistic mols. to cure various infectious diseases. Viruses are one of the major factors of human infectious diseases. Due to the increasing resistance to antiviral drug there is an urgent need to search for alternative agonistic compounds from plants. Plants are vital sources to induce innate immune system against viral disease. Interferon plays important role in innate immunity and mediates antiviral activity by inducing many interferon stimulating genes (ISGs) also called IFITs. ISGs block different stages of the virus replication, viral protein synthesis, and assembly of new virus particles. Among ISGs, ISG56, a component of innate immunity plays a critical role in mounting immune response against viruses. In this study, we screened plant extracts for their anti-viral properties by exploring their potential to induce ISG56 in cell culture rather than inhibition of viral protein function. Five medicinal plants were selected from NeMedPlant database. Out of the 5 ethnically known medicinal plants, Rheum emodi (RE) root extract was identified to induce ISG56 expression specifically. Therefore, the current study could provide an important insight into the development of a novel natural plant based anti-viral therapeutic from the RE extract without compromising on viral resistance. This study involved multiple reactions and reactants, such as 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one (cas: 524-12-9Electric Literature of C16H10O7).
1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one (cas: 524-12-9) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Electric Literature of C16H10O7
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem