Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Formula: C9H6O3. Introducing a new discovery about 496-41-3, Name is Benzofuran-2-carboxylic acid
Replacing the naphthalene C-unit of the anti-tuberculosis drug bedaquiline with a range of bicyclic heterocycles of widely differing lipophilicity gave analogs with a 4.5-fold range in clogP values. The biological results for these compounds indicate on average a lower clogP limit of about 5.0 in this series for retention of potent inhibitory activity (MIC90s) against M.tb in culture. Some of the compounds also showed a significant reduction in inhibition of hERG channel potassium current compared with bedaquiline, but there was no common structural feature that distinguished these.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C9H6O3, you can also check out more blogs about496-41-3
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1979O – PubChem