87-41-2, Isobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Isobenzofuran-1(3H)-one (6.6 g, 49.6 mmol), NBS (9.7 g,54.5 mmol) and AIBN (0.8 g, 4.9 mmol) were diluted in dry carbon tetrachloride (CCl4) (200 mL) and heated to72C for 2.5h. The mixture was cooled to room temperatureovernight, filtered, and the residue was washed withpetroleum ether. The filtrate was concentrated in vacuo toprovide the crude product, which was recrystallized fromcyclohexane to give 2 (8.6 g, 81.8%) as a light brown solid;m. p. 79-82C (lit. [24]: 76-78C). – 1H NMR (600MHz,CDCl3): =7.65 (d, 1H, J=7.2Hz), 7.80-7.77 (m, 1H), 7.64-7.61(m, 2H), 7.41 (s, 1H). – 13C NMR (150MHz, CDCl3): =167.3,148.8, 135.2, 130.9, 125.9, 124.0, 123.5, 74.6.
87-41-2, 87-41-2 Isobenzofuran-1(3H)-one 6885, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Article; Fan, Lingling; Luo, Bilan; Luo, Zhongfu; Zhang, Li; Fan, Judi; Xue, Wei; Tang, Lei; Li, Yong; Zeitschrift fur Naturforschung, B: Chemical Sciences; (2019);,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem