Palladium-catalyzed direct C-H arylation of pyridine N-oxides with potassium aryl- and heteroaryltrifluoroborates was written by Li, Mengli;Li, Xing;Chang, Honghong;Gao, Wenchao;Wei, Wenlong. And the article was included in Organic & Biomolecular Chemistry in 2016.Electric Literature of C8H5BF3KO This article mentions the following:
An efficient ligand-free Pd(OAc)2-catalyzed selective arylation of pyridine N-oxides, e.g. pyridine N-oxide, using potassium (hetero)aryltrifluoroborates as coupling partners via C-H bond activation was achieved in the presence of TBAI to give the corresponding aryl pyridine oxides,, e.g. I. This approach has a broad substrate scope and shows moderate to high yields. In the experiment, the researchers used many compounds, for example, Potassium benzofuran-2-yltrifluoroborate (cas: 929626-27-7Electric Literature of C8H5BF3KO).
Potassium benzofuran-2-yltrifluoroborate (cas: 929626-27-7) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Electric Literature of C8H5BF3KO
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem